Amyopathic dermatomyositis (dermatomyositis siné myositis)
Identifieur interne : 002F85 ( Main/Exploration ); précédent : 002F84; suivant : 002F86Amyopathic dermatomyositis (dermatomyositis siné myositis)
Auteurs : Rebecca L. Euwer [États-Unis] ; Richard D. Sontheimer [États-Unis]Source :
- Journal of the American Academy of Dermatology [ 0190-9622 ] ; 1991.
English descriptors
- Teeft :
- Acad dermatol, American academy, Amyopathic, Amyopathic dermatomyositis, Amyopathic dermatomyositis patients, Biopsy, Bohan, Clin dermatol, Corticosteroid, Cutaneous, Cutaneous findings, Cutaneous manifestations, Dermatol, Dermatology, Dermatology euwer, Dermatomyositis, Dermatomyositis sin6 myositis, Eruption, Erythema, Histopathologic characteristics, Hydroxychloroquine, Inflammation, Krain, Lupus erythematosus, Muscle disease, Muscle enzymes, Muscle involvement, Muscle weakness, Myositis, Papule, Pediatric patient, Periungual, Polymyositis, Prednisone, Pulmonary fibrosis, Residual muscle disease, Skin disease, Skin inflammation, Sontheimer, Symptomatic skin disease, Violaceous, Violaceous discoloration.
Abstract
We report six patients with the classic cutaneous findings of dermatomyositis who did not develop clinical or laboratory evidence of muscle disease for at least 2 years after onset of then-skin manifestations. Such patients represent 11% of our total experience with dermatomyositis patients during a 15 year period. All six patients had Gottron's paules, periungual erythema/telangiectasia, and violaceous discoloration of the face, neck, upper chest, and back at some time during the course of their disease. In addition, all complained of pruritus and photosensitivity. None of the patients had evidence of malignancy. Each of five patients treated with oral corticosteroids for their cutaneous disease had marked improvement and did not develop myositis. These cases further emphasize that the cutaneous manifestations of dermatomyositis are pathognomonic of this disease and challenge the commonly held notion that muscle disease always develops within 2 years of onset of skin disease.
Url:
DOI: 10.1016/0190-9622(91)70153-S
Affiliations:
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Euwer</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>From the Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Sontheimer, Richard D" sort="Sontheimer, Richard D" uniqKey="Sontheimer R" first="Richard D." last="Sontheimer">Richard D. Sontheimer</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>From the Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>From the Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Reprint requests: R. D. Sontheimer, MD, Department of Dermatology, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of the American Academy of Dermatology</title><title level="j" type="abbrev">YMJD</title><idno type="ISSN">0190-9622</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1991">1991</date><biblScope unit="volume">24</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="supplement">P1</biblScope><biblScope unit="page" from="959">959</biblScope><biblScope unit="page" to="966">966</biblScope></imprint><idno type="ISSN">0190-9622</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0190-9622</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acad dermatol</term><term>American academy</term><term>Amyopathic</term><term>Amyopathic dermatomyositis</term><term>Amyopathic dermatomyositis patients</term><term>Biopsy</term><term>Bohan</term><term>Clin dermatol</term><term>Corticosteroid</term><term>Cutaneous</term><term>Cutaneous findings</term><term>Cutaneous manifestations</term><term>Dermatol</term><term>Dermatology</term><term>Dermatology euwer</term><term>Dermatomyositis</term><term>Dermatomyositis sin6 myositis</term><term>Eruption</term><term>Erythema</term><term>Histopathologic characteristics</term><term>Hydroxychloroquine</term><term>Inflammation</term><term>Krain</term><term>Lupus erythematosus</term><term>Muscle disease</term><term>Muscle enzymes</term><term>Muscle involvement</term><term>Muscle weakness</term><term>Myositis</term><term>Papule</term><term>Pediatric patient</term><term>Periungual</term><term>Polymyositis</term><term>Prednisone</term><term>Pulmonary fibrosis</term><term>Residual muscle disease</term><term>Skin disease</term><term>Skin inflammation</term><term>Sontheimer</term><term>Symptomatic skin disease</term><term>Violaceous</term><term>Violaceous discoloration</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">We report six patients with the classic cutaneous findings of dermatomyositis who did not develop clinical or laboratory evidence of muscle disease for at least 2 years after onset of then-skin manifestations. Such patients represent 11% of our total experience with dermatomyositis patients during a 15 year period. All six patients had Gottron's paules, periungual erythema/telangiectasia, and violaceous discoloration of the face, neck, upper chest, and back at some time during the course of their disease. In addition, all complained of pruritus and photosensitivity. None of the patients had evidence of malignancy. Each of five patients treated with oral corticosteroids for their cutaneous disease had marked improvement and did not develop myositis. These cases further emphasize that the cutaneous manifestations of dermatomyositis are pathognomonic of this disease and challenge the commonly held notion that muscle disease always develops within 2 years of onset of skin disease.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Texas</li></region></list><tree><country name="États-Unis"><region name="Texas"><name sortKey="Euwer, Rebecca L" sort="Euwer, Rebecca L" uniqKey="Euwer R" first="Rebecca L." last="Euwer">Rebecca L. Euwer</name></region><name sortKey="Sontheimer, Richard D" sort="Sontheimer, Richard D" uniqKey="Sontheimer R" first="Richard D." last="Sontheimer">Richard D. Sontheimer</name><name sortKey="Sontheimer, Richard D" sort="Sontheimer, Richard D" uniqKey="Sontheimer R" first="Richard D." last="Sontheimer">Richard D. Sontheimer</name><name sortKey="Sontheimer, Richard D" sort="Sontheimer, Richard D" uniqKey="Sontheimer R" first="Richard D." last="Sontheimer">Richard D. 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